In this study, we contribute to the innovation and acquisition literatures by investigating the impact of Chief Innovation Officers (CINO) on post-acquisition innovation efforts. We propose that CINOs have distinct benefits for innovation focused organizations, especially those pursuing technology intensive acquisitions. We further investigate the conditions surrounding technology intensive acquisitions, suggesting that the presence of CINOs in the targeted firm and investments into innovation following acquisitions moderate the impact of the acquiring firm having a CINO. Collectively, we find evidence supporting our predictions. Our findings offer theoretical contributions by demonstrating the value of CINOs in the management of technology focused acquisitions. Further, this study offers practical contributions for organizations pursuing acquisitions with the intent of augmenting their existing innovation capabilities by demonstrating the importance of structural or management related fit between merging organizations and post-acquisition management of strategic resources.