Inclusive management has garnered significant attention, yet literature has explored less the organizational inclusion with interaction of different work arrangements to achieve organizational effectiveness. Using the data from federal employees in the US, this study examines the effects of inclusive leadership on organizational performance, which is mediated by inclusive climate. It also investigates the moderating role of different work arrangements in the relationship between inclusive leadership and climate. The results demonstrate the positive association between inclusive leadership and organizational performance, which is significantly mediated by inclusive climate. Findings also highlight that the positive relationship between inclusive leadership and climate is pronounced with greater workplace flexibility. This study advances the comprehensive framework of inclusive management accounting for leadership and organizational climate under different work arrangements. The practical implications from this study will benefit public administrators and inform inclusive management practices in post-pandemic work environments.